Wednesday, March 13, 2013

II Regulation of Muscle Contraction
A. The Motor Cortex of the brain (Kenzie) releases motor impulse (Erin) down pathway leading to target muscle
B. It reaches the Synaptic Knob (Bryan) where a Neurotransmitter (Ach-Brennan) is released into the Neuromuscular Junction - the synapse between nerve and muscle
C. Ach bonds to receptor sites on the Sarcoplasmic Reticulum (SR-Holden) Membrane which surrounds and permeates muscle and also holds a resting charge. The SR will now "fire" and release Ca2+ (Carson) ions into the muscle fibers.
D. Ca2+ will now bond to Troponin (Maddie). Troponin is a smaller protein found along the length of a larger, cable-like, protein called Tropomyosin.
E. This causes the Tropomyosin cable to shift position exposing the Actin Binding Sites (Rachel) to the Myosin Heads (Bryar). RESULT: CONTRACTION.
NOTE: The regulation of Muscle Contraction (strength and duration) is directly controlled by the amount of Ca2+ that are bonded to Troponin molecules at any one time.

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